The intestinal epithelium forms a continuous physical and functional barrier that protects the internal environment of the body from the fluctuating external input. Various substances including dietary elements, gastrointestinal secretory products, and xenobiotics are known to disrupt this epithelial barrier, leading to the shedding of epithelial cells and the development of digestive upset and discomfort. Saccharomyces boulardii is a probiotic yeast that helps to support intestinal health by encouraging a balanced response by the intestinal epithelium to normal metabolic stress, as well as through its effects on overall gut ecology.* Saccharomyces boulardii has been clinically shown to support gastrointestinal health during temporary disruptions in the normal balance of gut flora.*